Inputs are validated to ensure they produce the expected results when given as the input in
simulate_trials()
. Therefore, any arguments to this function can also be just a single value
(except the arms
argument), and this function will expand such single-valued arguments to be
compatible with simulate_trials()
. If arguments are named vectors, they must have exactly one
value per arm, and the names must match those given in the arms
.
Usage
setup_scenario(
arms = NULL,
n_patients = NULL,
index_hrqol = NULL,
first_hrqol = NULL,
final_hrqol = NULL,
acceleration_hrqol = NULL,
mortality = NULL,
mortality_dampening = NULL,
mortality_trajectory_shape = NULL,
prop_mortality_benefitters = NULL,
sampling_frequency = NULL,
verbose = TRUE
)
Arguments
- arms
character vector with the names of the arms
- n_patients
named integer (single value or named vector), number of patients
- index_hrqol
numeric (single value or named vector), the HRQoL at index (= enrolment)
- first_hrqol
numeric (single value or named vector), the HRQoL at ICU discharge in each arm
- final_hrqol
numeric (single value or named vector), the HRQoL at end of follow-up in each arm
- acceleration_hrqol
numeric (single value or named vector), relative acceleration of HRQoL improvement in each arm
- mortality
numeric (single value or named vector) in
[0, 1]
, the mortality in at end of follow-up, in each arm- mortality_dampening
numeric (single value or named vector), dampening effect on HRQoL at ICU discharge in patients who die before end of follow-up
- mortality_trajectory_shape
character (single value or named vector), valid values are
"exp_decay"
(default),"linear"
,"constant"
,"reflected_exp_decay"
and can differ across arms.- prop_mortality_benefitters
numeric (single value or named vector)
[0, 1]
, the proportion of patients in each arm who are so-called mortality benefitters- sampling_frequency
integer (single value or named vector), span between HRQoL sampling from patients
- verbose
single logical, should the function provide detailed output on validation results? Default:
TRUE